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In 2021, Cognition Therapeutics completed two important clinical study trials. The first was SNAP which measured the displacement of amyloid beta oligomers into the cerebrospinal fluid (CSF). This study confirmed the mechanism of action of their lead candidate CT1812. CT1812 is orally delivered and designed to bind selectively to the sigma-2 receptor complex to restore damaged cellular processes. The second trial, SPARC, showed evidence that CT1812 slowed brain atrophy in mild-to-moderate Alzheimer patients. Currently, there are 7 ongoing clinical trials with CT1812. Cognition Therapeutics has also achieved over $117 million in funding from the National Institute on Aging. Lisa Ricciardi, CEO, and president of Cognition Therapeutics reported, “2021 was a transformative year for Cognition Therapeutics. We completed our IPO, secured significant additional non-dilutive funding, and progressed our pipeline creating a product portfolio in addition to our lead candidate CT1812.”

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